PDZPepInt is a cluster based prediction tool to predict binding peptides of PDZ domains in human, mouse, fly and worm. Total 43 built-in models that cover 226 PDZ domains across the species are available. Peptides are represented as 5 C-terminal sequences of binding proteins. Depending on the user requirement Gene Ontology database can be used for getting reliable interactions. Additionally, it will also consider the C-terminal peptides that are intrinsically unstructured for getting high confidence interactions.
PDZPepInt - PDZ Interactions
When using PDZPepInt please cite :
- Kousik Kundu, Martin Mann, Fabrizio Costa, and Rolf Backofen
MoDPepInt: An interactive webserver for prediction of modular domain-peptide interactions
Bioinformatics, 2014, in press.
- Kousik Kundu and Rolf Backofen
Cluster based prediction of PDZ-peptide interactions
BMC Genomics, 15 Suppl 1 pp. S5, 2014.
Results are computed with PDZPepInt version 1.0.0