MoDPepInt Server
SH2PepInt - SH2 Interactions
BIF
IFF
SH2PepInt

SH2PepInt - SH2 Interactions

SH2PepInt has been developed to predict binding partners of 51 human SH2 domains. Peptides are restrained to 7 amino acids length, i.e. -2 to +4 amino acids around the pTyr position. Depending on the user requirement it uses PhosphoSitePlus and Gene Ontology databases for predicting highly reliable SH2-peptide interactions.

For articles describing the tool refer to the reference section below. Please cite us when using our tools.
For more information check the help page.

Try SH2PepInt with this example: SH2 interactions (input|result) ?

Input Parameters

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Note: Filters require UniProt IDs along with all targeted protein sequences in the FASTA input (check enabled filters).
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? SH2 Domains: select [all] [none]

Filters select [all] [none]

Note: Filters require UniProt IDs along with all targeted protein sequences in the FASTA input (check enabled filters).
? Phosphotyrosine (pY) (needs UniProt IDs):
? Cellular localization (needs UniProt IDs):

Train with your own data

In case you want to use your own data to make a dedicated SH2-prediction model, please contact us.

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When using SH2PepInt please cite :

Results are computed with SH2PepInt version 1.0.0