SH2PepInt has been developed to predict binding partners of 51 human SH2 domains. Peptides are restrained to 7 amino acids length, i.e. -2 to +4 amino acids around the pTyr position. Depending on the user requirement it uses PhosphoSitePlus and Gene Ontology databases for predicting highly reliable SH2-peptide interactions.

For articles describing the tool and webserver refer to the reference section below. Please cite us when using our tools.
For more information check the help page.

• Kousik Kundu, Martin Mann, Fabrizio Costa, and Rolf Backofen
  MoDPepInt: An interactive webserver for prediction of modular domain-peptide interactions
  Bioinformatics, 2014, in press.
  
• Kousik Kundu, Fabrizio Costa, Michael Huber, Michael Reth, and Rolf Backofen
  Semi-Supervised Prediction of SH2-Peptide Interactions from Imbalanced High-Throughput Data
  PLoS One, 8(5), pp. e62732, 2013.