[Download]
the following interaction table
Input and runtime details for job 8167883 (precomputed example)
Input Parameters
| Protein/Peptide FASTA | [.fa] | ||
| Protein UniProt IDs | [.fa] | ||
| SH2 Domains | CRKL, CRK, GRB2 |
Filters
| Phosphotyrosine (pY) (needs UniProt IDs) | yes | ||
| Cellular localization (needs UniProt IDs) | yes |
Job ID 8167883 (server version 4.2.2)
 | Job Submitted & Queued | @ Fri Jul 22 10:48:34 CEST 2016 | |
| SH2PepInt Started | @ Fri Jul 22 10:48:42 CEST 2016 | |
| SH2PepInt Finished & Post-Processing | @ Fri Jul 22 10:49:36 CEST 2016 | |
| Job Completed | @ Fri Jul 22 10:49:39 CEST 2016 |
DIRECT ACCESS: https://modpepint.informatik.uni-freiburg.de/RetrieveResults.jsp?jobID=8167883&toolName=SH2PepInt ( 30 days expiry )
Description of the job
This is an example for the interaction prediction of human SH2 domains from GRB2, CRK and CRKL proteins with the target proteins ERBB1, ERBB2 and ERBB3.
Output download complete results [zip]
Sort by selecting a column name.
| Sequence ID | Position | Sequence | Domain |
|---|---|---|---|
| sp|P00533|EGFR_HUMAN | pY112 | NMYYENS | CRKL, CRK |
| sp|P00533|EGFR_HUMAN | pY585 | AHYIDGP | GRB2 |
| sp|P00533|EGFR_HUMAN | pY944 | DVYMIMV | CRK |
| sp|P00533|EGFR_HUMAN | pY998 | NFYRALM | CRK |
| sp|P00533|EGFR_HUMAN | pY1016 | DEYLIPQ | CRKL, CRK |
| sp|P00533|EGFR_HUMAN | pY1092 | PEYINQS | GRB2 |
| sp|P00533|EGFR_HUMAN | pY1110 | PVYHNQP | GRB2 |
| sp|P00533|EGFR_HUMAN | pY1125 | PHYQDPH | CRKL, CRK |
| sp|P00533|EGFR_HUMAN | pY1138 | PEYLNTV | GRB2 |
| sp|P00533|EGFR_HUMAN | pY1197 | AEYLRVA | CRKL, CRK |
| P04626 | pY1005 | TFYRSLL | CRK |
| P04626 | pY1023 | EEYLVPQ | CRKL, CRK |
| P04626 | pY1127 | DGYVAPL | CRKL, CRK |
| P04626 | pY1139 | PEYVNQP | GRB2 |
| P04626 | pY1222 | LYYWDQD | CRKL |
Job resubmission
Use the following button if you want to resubmit the job with
altered input or parameterization:
usability assessment
When using SH2PepInt please cite :
- Kousik Kundu, Martin Mann, Fabrizio Costa, and Rolf Backofen
MoDPepInt: An interactive webserver for prediction of modular domain-peptide interactions
Bioinformatics, 2014, in press. - Kousik Kundu, Fabrizio Costa, Michael Huber, Michael Reth, and Rolf Backofen
Semi-Supervised Prediction of SH2-Peptide Interactions from Imbalanced High-Throughput Data
PLoS One, 8(5), pp. e62732, 2013.
Results are computed with SH2PepInt version 1.0.0
About this web server
|
version 5.0.10
|
Copyright © 2012 - 2025 Bioinformatics Group Freiburg
|
|
Imprint and Disclaimer
|
Imprint and Disclaimer